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年龄相关性黄斑变性的病因学研究进展

http://www.cnophol.com 2009-6-16 11:15:34 中华眼科在线

14 Tan JS, Wang JJ, Liew G, et al. Agerelated macular degeneration and mortality from cardiovascular disease or stroke. Br J Ophthalmol 2008;92(4):509512

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21 SanGiovanni JP, Chew EY, Clemons TE, et al. The relationship of dietary carotenoid and vitamin A, E, and C intake with agerelated macular degeneration in a casecontrol study: AREDS Report No. 22. Arch Ophthalmol 2007;125(9):12251232

22 Souied EH, Leveziel N, Richard F, et al. Y402H complement factor H polymorphism associated with exudative agerelated macular degeneration in the French population. Mol Vis 2005;11:11351140

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24 Lau LI, Chen SJ, Cheng CY, et al. Association of the Y402H polymorphism in complement factor H gene and neovascular agerelated macular degeneration in Chinese patients. Invest Ophthalmol Vis Sci 2006;47(8):32423246

25 Gotoh N, Yamada R, Hiratani H, et al. No association between complement factor H gene polymorphism and exudative agerelated macular degeneration in Japanese. Hum Genet 2006;120(1):139143

26 Yates JR, Sepp T, Matharu BK, et al. Complement C3 variant and the risk of agerelated macular degeneration. N Engl J Med 2007;357(6):553561

27 MullerEberhard HJ. Molecular organization function of the complement system. Annu Rev Biochem 1988;57:321347

28 Sivaprasad S,Adewoyin T,Bailey TA, et al. Estimation of systemic complement C3 activity in agerelated macular degeneration. Arch Ophthalmol 2007;125(4):515519

29 Maller J, George S, Purcell S, et al. Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of agerelated macular degeneration. Nat Genet 2006;38(9):10551059

30 Jakobsdottir J, Conley YP, Weeks DE, et al. C2 and CFB genes in agerelated maculopathy and joint action with CFH and LOC387715 genes. PLoS ONE 2008;3(5):e2199

31 Gibbs D, Yang Z, Constantine R, et al. Further mapping of 10q26 supports strong association of HTRA1 polymorphisms with agerelated macular degeneration. Vision Res 2008;48(5):685 689

32 Yang Z, Camp NJ, Sun H, et al. A variant of the HTRA1 gene increases susceptibility to agerelated macular degeneration. Science 2006;314(5801):992993

33 Dewan A, Liu M, Hartman S, et al. HTRA1 promoter polymorphism in wet agerelated macular degeneration. Science 2006;314(5801):989992

34 Cameron DJ, Yang Z, Gibbs D, et al. HTRA1 variant confers similar risks to geographic atrophy and neovascular agerelated macular degeneration. Cell Cycle 2007;6(9):11221125

35 Rivera A, Fisher SA, Fritsche LG, et al. Hypothetical LOC387715 is a second major susceptibility gene for agerelated macular degeneration, contributing independently of complement factor H to disease risk. Hum Mol Genet 2005;14(21):32273236

36 Franke TF, Hornik CP, Segev L, et al. PI3K/Akt and apoptosis: size matters. Oncogene 2003;22(56):8983 8998

37李夏,王雨生.Pega治疗湿性年龄相关性黄斑变性的临床研究.国际眼科杂志2006;6(4):829 832

38 Richardson AJ, Islam FM, Guymer RH, et al. A tagsingle nucleotide polymorphisms approach to the vascular endothelial growth factorA gene in agerelated macular degeneration. Mol Vis 2007;13:21482152

39 Lin JM,Wan L,Tsai YY, et al. Vascular endothelial growth factor gene polymorphisms in agerelated macular degeneration. Am J Ophthalmol 2008;145(6):10451051

40 Tsimikas S, Willerson JT, Ridker PM. Creactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients. J Am Coll Cardiol 2006;47(8 Suppl):C1931

41 Schaumberg DA, Christen WG, Kozlowski P, et al. A prospective assessment of the Y402H variant in complement factor H, genetic variants in Creactive protein, and risk of agerelated macular degeneration. Invest Ophthalmol Vis Sci 2006;47(6):23362340

42 Kikuchi M, Nakamura M, Ishikawa K, et al. Elevated Creactive protein levels in patients with polypoidal choroidal vasculopathy and patients with neovascular agerelated macular degeneration. Ophthalmology 2007;114(9):17221727

43 Johnson PT, Betts KE, Radeke MJ, et al. Individuals homozygous for the agerelated macular degeneration riskconferring variant of complement factor H have elevated levels of CRP in the choroid. Proc Natl Acad Sci USA 2006;103(46):1745617461

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