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4展望
综上所述，C肽在防治糖尿病其它并发症过程中发挥重要作用，而在C肽与DR方面，研究远不如糖尿病其它并发症深入。从一般意义上讲，C肽是胰岛β细胞正常分泌的一种多肽类物质，对DR的发展不应发挥促进作用。而有关C肽受体在视网膜各层的表达情况；C肽在其受体表达阳性细胞的作用机理，即是否存在Na+K+ATPase活性增高及NO合成增加；C肽替代性治疗对于DR发生发展的影响，包括：视网膜的病理变化，超微结构的改变，视网膜一氧化氮合酶（NOS）含量的变化等均未清楚。并且C肽与其受体结合后能使NO合成增加，按照目前多数学者的观点，NO合成增加对于DR的发展是起到促进作用的。因此非常有必要对C肽在DR中的所发挥的作用及其机理进一步深入研究。
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