巩膜扣带术后角膜内皮细胞形态学的改变
顾永昊，柯根杰，潘红飙
作者单位：（230001）中国安徽省合肥市，安徽医科大学附属省立医院眼科
作者简介：顾永昊，男，主治医师，博士。
通讯作者：顾永昊[email protected]
收稿日期：2008-02-14修回日期：2008-05-05
Morphologic changes of corneal endothelium after scleral buckling
Yong-Hao Gu, Gen-Jie Ke, Hong-Biao Pan
Department of Ophthalmology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, Anhui Province, China
Correspondence to: Yong-Hao Gu. Department of Ophthalmology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, Anhui Province, China. [email protected]
Received:2008-02-14Accepted:2008-05-05
Abstract
AIM: To investigate the influence of scleral buckling on corneal endothelium.
METHODS: Seventy-two cases (72 eyes) of rhegma-togenous retinal detachment were treated with scleral buckling. Intraocular pressure, endothelial cell density, hexagonalilty, coefficient of variation of cell area were measured before surgery and 1, 3, 5, 15 days after surgery.
RESULTS: Compared with preoperative data, intrao-cular pressure and coefficient of variation of cell area were significantly elevated 1 and 3 days after surgery（P<0.05）and had no obvious correlation（P>0.05）. There was no significant difference for endothelial cell density and hexagonalilty before and after surgery（P>0.05）.
CONCLUSION: There is transient influence of scleral buckling on corneal endothelium, which might due to change of cell metabolism and can recover a half month after surgery.
KEYWORDS: scleral buckling; corneal endothelium; intraocular pressure
Gu YH,Ke GJ,Pan HB.Morphologic changes of corneal endothelium after scleral buckling. Int J Ophthalmol（Guoji Yanke Zazhi）2008;8(6):1198-1199
摘要
目的：研究巩膜扣带术对角膜内皮细胞的影响。
方法：原发性视网膜脱离患者72例（72眼）行巩膜外垫压联合环扎术，分别在术前、术后1，3，5，15d测量眼压、角膜内皮细胞密度、六角形细胞比例和变异系数。
结果：与术前相比，术后1d和3d的眼压及角膜内皮细胞变异系数都显著性增加（P<0.05），之后降低，与术前无显著性差异（P>0.05），两者之间也无明显相关性（P>0.05）。角膜内皮细胞密度和六角形细胞比例在术前和术后各时间之间均无明显差异（P>0.05）。
结论：巩膜扣带术对角膜内皮细胞影响较小，仅使变异系数发生一过性改变，可能与细胞代谢过程受影响有关，术后0.5mo左右恢复。
关键词：巩膜扣带术；角膜内皮细胞；眼压
顾永昊，柯根杰，潘红飙.巩膜扣带术后角膜内皮细胞形态学的改变.国际眼科杂志2008;8(6):1198-1199 |
