【摘要】 目的 评价白内障患者蓝光滤过型人工晶状体ＡＣＲＹｓｏｆｔＴＭ ｎａｔｕｒａｌ ＩＯＬ植入术后视功能的改变。方法 采用临床对照研究，连续收集年龄相关性白内障患者４７例（４７眼），随机分为两组，均行超声乳化加人工晶状体植入术，观察组植入ＡＣＲＹｓｏｆｔＴＭ ｎａｔｕｒａｌ ＩＯＬ（Ａｌｃｏｎ，ＳＮ６０ＡＴ），对照组植入非蓝光滤过型人工晶状体ＡＣＲＹｓｏｆｔＴＭ Ｓｉｎｇｌｅ－Ｐｉｅｃｅ ＩＯＬ（Ａｌｃｏｎ，ＳＡ６０ＡＴ）。于术后不同时间点检查视力、波前像差及对比敏感度，随访时间为６个月。结果 观察组与对照组术后第３个月和第６个月波前像差差异无显著性；观察组空间对比敏感度在中、低频率上明显高于对照组。结论 在白内障术后早期阶段，蓝光滤过型人工晶状体ＡＣＲＹｓｏｆｔＴＭ ｎａｔｕｒａｌ ＩＯＬ与非蓝光滤过型人工晶状体ＡＣＲＹｓｏｆｔＴＭ Ｓｉｎｇｌｅ－Ｐｉｅｃｅ ＩＯＬ相比，其可以提高患者空间对比敏感度，而波前像差无明显改变。
【关键词】 蓝光；晶体，人工；波前像差；对比敏感度；超声乳化
A clinic study of visual function after ACRYsoft natural intraocular lens
LI Guoxing, SONG Huiyang, WANG Qinmei, et al.
Eye Hospital of Wenzhou Medical College,Wenzhou China,325027
[Abstract] Objective To evaluate wavefront aberrations and contrast sensitivity of ACRYsoftTM natural IOL in cataract patients. Methods Routine phacoemulsification and IOL implantation were performed in 47 senile cataract patients. The patients were randomly assigned to receive 23 ACRYsoftTM natural IOLs and 24 ACRYsoftTM Single-Piece IOLs. Visual acuity, wavefront aberrations and contrast sensitivity examined up to 6 months postoperatively. Results The ACRYsoftTM natural IOLs showed statistically significantly higher spatial contrast sensitivity than ACRYsoftTM Single-Piece IOLs in the low and middle frequencies. There was no significant difference between blue light filtering IOLs and ordinary UV IOL in wavefront aberrations. Conclusions Blue light filtering ACRYsoftTM natural IOLs are preferable to ordinary UV IOLs in preserving spatial contrast sensitivity in the early postoperative period，but not change wavefront aberrations.
[Key words] blue light； lens, intraocular； wavefront aberrations； contrast sensitivity； phacoemulsification
蓝光对视网膜尤其是黄斑的光损伤逐渐受到人们的重视。在自然年龄的变化进程中，人眼晶状体逐渐变成黄色，在一定程度上避免了蓝光对视网膜的损伤。蓝光滤过型人工晶状体植入后的透过光谱接近人眼晶状体的透过光谱，理论上存在保护视网膜免受蓝光损伤的功能。２０世纪９０年代日本研制的聚甲基丙烯酸酯材料的蓝光滤过型人工晶状体，其载色基团是以非共价键结合方式结合，染色物质容易析出。Ａｌｃｏｎ公司生产的蓝光滤过型人工晶状体ＡＣＲＹｓｏｆｔＴＭ ｎａｔｕｒａｌ ＩＯＬ（ＳＮ６０ＡＴ），其蓝光滤过载色基团是以共价键结合，可以防止染料的析出和释放，在滤过紫外线的同时可以滤过波长为４００～ ４７５ ｎｍ的蓝光。本研究评价该晶状体植入后人眼波前像差及对比敏感度的改变。
[1] [2] [3] [4] 下一页 |
